Charles-Edouard Brown-Séquard papers
Scope and Contents
This small collection contains three brief holograph manuscripts,
1890-1891, of C. E. Brown Sequard. Two of the manuscripts,
"Nouvelles remarques" and "Histoire et critique" concern the
therapeutic use of animal testicular extract as an aid to rejuvenation
and a specific against diseases such as tuberculosis. The third
manuscript, "De la perte de connaissance" concerns epilepsy.
All three manuscripts were published, "Nouvelles remarques"
in Comptes rendus hebdomadaires des seances
et memoires la Societe de Biologie (1890), the other
two in Archives de physiologiejnormale et
pathologie (1891).
The collection also includes an autographed letter signed
by Brown Sequard, 27 December 1890, conveying the three manuscripts
to S. Weir Mitchell.
Dates
- Creation: 1890 - 1891
Creator
- Brown-Séquard, Charles-Edouard (Person)
Biographical / Historical
Charles Edouard Brown Sequard, physiologist, was born on 8 April
1817 on Mauritius. He was married three times: to Ellen Fletcher
(d. 1868) by whom he had one son; in 1873 to Maria R. Carlisle
(d. 1875) by whom he had one daughter; and in 1878 to Elizabeth
Emma Dakin. Brown Sequard died on 1 April 1894.
Brown Sequard received a bachelor of letters and a bachelor of
science from the University of Paris, then received an M.D.
from the Ecole de Medecine in Paris in 1840. He traveled extensively
and held several teaching positions, including professor of
physiology at the Medical College of Virginia, 1855, professor
of physiology and pathology at Harvard University, 1864-1867,
and professor of comparative and experimental pathology at the
Ecole de Medecine in Paris, 1869-1871. In 1873, he was practicing
in New York, but in 1878 assumed the chair of experimental medicine
at the College de France. He also founded the Archives of scientific
and practical medicine.
In 1849, Brown Sequard discovered sensory decussation in the spinal
cord and worked for most of his life on diseases of the spinal
column, nervous system, and muscular system. In the last years
of his life, Brown Sequard developed the popular "Methode Sequardienne",
advocating the use of an extract of testicular fluid to rejuvenate
the body, cure certain diseases, and prolong life.
Brown Sequard was a Fellow of the Royal College of Physicians
of London, the Royal Society of England, and the American Academy
of Sciences.
Full Extent
1 folder
Language of Materials
French
Physical Location
Small collections
Custodial History
The three Brown Sequard manuscripts were donated to the College of Physicians of Philadelphia by S. Weir Mitchell of Philadelphia on 13 January 1891. On 27 December 1890, Brown Sequard himself sent the manuscripts to Mitchell, apparently at the latter's request, specifically for presentation to the College.
- Title
- Charles-Edouard Brown-Séquard papers
- Description rules
- Describing Archives: A Content Standard
- Language of description
- English
- Script of description
- Latin
Repository Details
Part of the Historical Medical Library of The College of Physicians of Philadelphia Repository
19 S. 22nd Street
Philadelphia PA 19103 United States


